Heart Disease Archive

A 2025 analysis of randomized trials found that cardiac rehab—a personalized program of supervised exercise and healthy lifestyle coaching—can also help people with atrial fibrillation, an irregular heartbeat that can cause stroke and heart failure.

The association between alcohol and cardiovascular disease is both complex and controversial. There’s no evidence of an increased risk for the most common forms of heart disease in people who stay within the limits for moderate drinking. Whether light to moderate drinking can lower a person’s risk is impossible to answer with currently available evidence. But there is clear, consistent evidence that heavier drinking—an average of three or more drinks per day—is linked to worse outcomes for every type of heart disease.

Getting vaccinated against influenza (flu), COVID-19, and pneumonia is especially important for people who have cardiovascular disease. The coughing and congestion that commonly occur with respiratory infections can make breathing more difficult, and the potential drop in oxygen puts added stress on the heart. Serious infections sometimes trigger sepsis, which happens when the immune system is overwhelmed or goes into overdrive, causing symptoms such as a rapid heart rate, very fast breathing, and low blood pressure. These complications can lead to a heart attack.

An inexpensive blood test that checks for a genetic variant of Lp(a)—a fatty particle similar to LDL cholesterol—may help clarify who might benefit from a daily low-dose aspirin, according to a 2025 review of study findings.

According to a 2025 study, people living near coastlines with high levels of marine microplastics had higher rates of heart disease than those living close to coastlines with less plastic pollution.

Growing numbers of people have microvascular disease, which is caused by problems in the network of tiny blood vessels in the heart rather than blockages in the heart’s major arteries. Evidence for this trend comes from large studies using diagnostic imaging tests coupled with heart disease registry data. Experts believe today’s higher rates of obesity, diabetes, high blood pressure, and chronic kidney disease is changing how cardiovascular disease is manifested.

In a 2025 analysis involving about 200 million people, those who used cannabis had a 29% higher risk for sudden heart attacks or angina and twice the risk of premature death from cardiovascular disease, compared with people who didn’t use cannabis.

There are no medications to treat aortic stenosis (narrowing of the aortic valve), but several possibilities are currently being studied, including a class of drugs to treat diabetes and others that lower high lipoprotein(a) blood levels.

A heart disease diagnosis may trigger a bout of depression. But having depression can also leave people more vulnerable to heart disease. Some of the overlap stems from shared lifestyle factors, such as inactivity and an unhealthy diet. In addition to addressing those issues, other safe and effective ways to ease depression include working with a therapist, using a light box, and taking medications.

If a blood clot lodges in an artery or vein, it can choke off blood flow to the heart, brain, or lung. Often called blood thinners, anti-clotting drugs play a big role in treating heart disease. But they can cause minor (and sometimes serious) bleeding, ranging from nosebleeds to bleeding inside the brain. New solutions to balance clot prevention and excess bleeding are in the works, including low-dose drug combinations and new medications.