Medications Archive

The stigma is fading, but learn the pros and cons before trying it.

Despite the hype and popularity of medical marijuana, you may not be sure if it's something to consider. You're right to be cautious; the use of marijuana to treat health problems is still being studied, and we don't have all the answers about its risks and benefits.

We do know that medical marijuana use among older adults is increasing. "Older adults tend to use it for physical ailments. No. 1 is chronic pain. Insomnia is another big one, too. Older people have a hard time sleeping, and there aren't a lot of other safe options," says Dr. Peter Grinspoon, a primary care physician with Harvard-affiliated Massachusetts General Hospital.

Normally associated with veterans, PTSD can also affect people of all ages who have experienced any kind of trauma.

Post-traumatic stress disorder (PTSD) is a severe and potentially debilitating mental health disorder that affects people who have experienced or witnessed a traumatic event. PTSD often occurs in combat veterans, but it can also strike older adults, and especially men.

About 70% of older men have been exposed to trauma at some point in life, according to the U.S. Department of Veterans Affairs. Many of these traumatic events are accidents (or near misses), injuries, or serious health issues.

News briefs

The United States is reporting increasing numbers of "deaths from despair" (suicide, drug overdose, or alcohol poisoning). Antidepressants and psychotherapy are often used to help people who are having a hard time coping with extremely difficult times and who are at risk for dying because of it. A recent Harvard study found that another strategy may also play a part in countering despair: attending religious services. The study, published online May 6, 2020, by JAMA Psychiatry, evaluated self-reported religious service attendance among 110,000 white, middle-aged men and women who were followed for about 30 years. Compared with never attending religious services, going at least once per week was associated with a much lower risk of death from despair: 68% lower for women and 37% lower for men. Researchers say that religious participation — regardless of affiliation — may serve as an antidote to despair and provide a sustained sense of hope, meaning, peace, and positive outlook. Also, faith-based organizations promote social engagement and connectedness and preach against self-injury and substance use. The study was observational and does not prove that regularly going to a religious service prevents death from despair. However, we know from other Harvard research that using religion to cope is associated with improved outcomes for people with severe psychiatric illness. Due to the pandemic, it may be difficult to attend your usual place of worship. Consider attending services via teleconference. If you attend in-person services, wear a mask and try to stay six feet away from others.

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Some common painkillers may boost the odds of a heart problem. Use them wisely to lessen your risk.

In 2004, the drug maker Merck pulled rofecoxib (Vioxx) off the market, following revelations that the popular prescription painkiller increased the risk of heart attacks and strokes. That action triggered a closer look at drugs in the same class, known as nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs, which are widely used to ease pain, quell inflammation, and cool fevers, include over-the-counter drugs such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn) and the prescription drug celecoxib (Celebrex).

Osteoarthritis pain can be debilitating. Strategies can help get you moving again.

Pain from osteoarthritis is more than just a nuisance. Knee pain, in particular, can not only keep people from exercising, but also have a chilling effect on their ability to participate in social activities, especially those that involve walking or traveling, says Elena Losina, the Robert W. Lovett Professor of Orthopedic Surgery at Harvard Medical School and co-director of the Orthopaedic and Arthritis Center for Outcomes Research at Brigham and Women's Hospital.

"In fact, the quality of life of a person with persistent pain due to knee osteoarthritis is similar to quality of life in women with metastatic breast cancer controlled by therapy," she says.

Before taking pills for a temporary situation, consider the risks.

You might think that using an antidepressant temporarily could help you weather a challenging time, such as a period of grief, extreme stress, or serious illness. But you shouldn't just jump into taking an antidepressant, cautions Dr. Jane Erb, psychiatric director of the Behavioral Health Integration in Primary Care Program at Harvard-affiliated Brigham and Women's Hospital.

"There's no evidence that taking an antidepressant in the short term will help or that it will prevent longer-term consequences of stress, such as post-traumatic stress disorder," she says.

Many children look forward to warm, mild spring weather, but kids with seasonal allergies (also known as hay fever) might not. Hay fever can interfere with a child's ability to play outdoors, and it can just plain make them feel miserable. These tips can help your child cope with allergy season — and they work just as well for adults, too.

New information may affect your approach to treatment.

Millions of people turn to prescription and over-the-counter medications to cope with heartburn from gastroesophageal reflux disease or other stomach conditions. But navigating the risks of heartburn remedies can leave a sour taste in your mouth, since some have been tied to health concerns. Here's what you need to know about two mainstays of treatment, and how the latest developments may affect you.

H2 blockers

Histamine₂-receptor antagonists, better known as H2 blockers — such as famotidine (Pepcid) and cimetidine (Tagamet) — are available over the counter or by prescription. They block a chemical that signals the stomach to produce acid, and are the go-to drugs when an antacid like calcium carbonate (Tums) or aluminum hydroxide (Maalox) isn't strong enough.

In the journals

Cholesterol-lowering statins and blood pressure drugs can improve heart health, but you still need to follow heart-healthy habits. That's the conclusion of a study published online Feb. 5, 2020, by the Journal of the American Heart Association, which found many people forgo healthy habits after they begin taking these medications.

Researchers in Finland identified 41,225 people who were free of cardiovascular disease. They collected such health data as body mass index, physical activity, alcohol intake, smoking status, and whether the people took statins or blood pressure drugs. Updated information was gathered from surveys every four years over a 14-year period.

Here's what the numbers mean — and strategies to lower your cholesterol if it's too high.

For some women who've had normal cholesterol readings all their lives, that changes at menopause. "Going through menopause often results in lipid and cholesterol changes for the worse," says Dr. Samia Mora, an associate professor of medicine at Harvard Medical School and a specialist in cardiovascular medicine the Brigham and Women's Hospital. Drops in the female hormone, estrogen, are associated with a rise in total cholesterol levels due to higher amounts of low-density lipoprotein (LDL), the "bad" cholesterol, and another blood lipid (fat) known as triglyceride. Over time this can raise heart risks, which is a reason for concern, as cardiovascular disease is the No. 1 cause of death in postmenopausal women, says Dr. Mora.

"So, it's especially important to track the numbers in perimenopause and the early years after menopause, as LDL cholesterol and total cholesterol tend to increase," she says.