Nerve disorders Archive

Burning mouth syndrome affects about 2% of people, with women up to seven times more likely than men to be diagnosed. Symptoms include burning sensations in the lips, mouth, or throat as well as stabbing pain, tingling, a sour or metallic taste, or the sense that something is crawling inside the mouth. Women’s hormone dips during perimenopause and beyond may play a role in the condition, and stress and anxiety are also considered risk factors. To confirm the diagnosis, doctors must first rule out other potential causes of symptoms.

In its 2025 guidelines for treating restless legs syndrome (RLS), the American Academy of Sleep Medicine stopped recommending the long-term use of dopamine agonist drugs, since they can eventually make RLS symptoms worse. Instead, the guidelines strongly recommend another class of medications as the first-line treatment: alpha-2-delta ligands, such as gabapentin (Neurontin), gabapentin enacarbil (Horizant), and pregabalin (Lyrica). Alpha-2-delta ligands do not make RLS symptoms worse.

Carpal tunnel syndrome is caused by increased pressure within the carpal tunnel, a narrow passage in the wrist containing the median nerve and tendons that run into the hand. The condition can lead to persistent tingling and numbness in the hands.

A 2024 study of people with sciatica caused by a herniated disk found that people who received acupuncture for 10 sessions over four weeks had less leg pain and better physical function, compared with people who received sham treatments.