Diseases & Conditions Archive

These uterine tumors, though usually benign, can cause heavy bleeding, cramps, and pregnancy complications. But there are several good options for treatment.

Fibroids—smooth muscle tumors of the uterus—are common, affecting as many as 75% of women. They are rarely cancerous, and they cause symptoms in only about 20% of the women who have them. However, if you're one of those with symptoms like heavy menstrual bleeding, bad cramps, pelvic pressure, constipation, or frequent urination, you know how fibroids can disrupt your life. Even if they don't cause symptoms, they may grow into the uterine cavity, potentially complicating a pregnancy and raising the risk of miscarriage.

"Managing uterine fibroids depends on several factors, such as a woman's symptoms, whether or not she wants to have children, her age, and her personal preferences," says Dr. Hye-Chun Hur, director of the Division of Minimally Invasive Gynecologic Surgery at Harvard-affiliated Beth Israel Deaconess Medical Center and associate medical editor of Harvard Women's Health Watch.

A Spanish clinical trial of 400 people—two-thirds of whom were women—has indicated that waiting to fill an antibiotic prescription may be a good idea for people with sniffles, coughs, sore throats, and other respiratory symptoms.

Researchers recruited volunteers who sought care for respiratory symptoms in primary care clinics throughout Spain. The volunteers were randomly assigned to four equal groups. One was given antibiotics and told to take them immediately. Another was sent home without antibiotics but told to return to the clinic if they hadn't improved after several days. The two remaining groups were told to wait to take antibiotics—one was asked to return to the clinic to get their mediation after three days; the other group was given an antibiotic, but told to take the medication only if their symptoms hadn't improved after five to 10 days.

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Tau proteins, and not necessarily beta-amyloid, may be the key to unlocking a viable treatment.

Alzheimer's disease affects more than five million people, and that number is expected to more than double by 2050. While there is no cure, attention has refocused on what many researchers believe is a major player in Alzheimer's: tau proteins.

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Is heart disease in your genes? And if so, can you do anything about it?

Cardiovascular disease continues to be the No. 1 killer of men, and while strides have been made to reduce the risk of heart attack and stroke, one area that remains elusive is genetics.

This common inflammation of the joints can be treated and managed with medication and lifestyle changes.

Gout affects more than eight million adults, six million of whom are men. It often strikes suddenly, like flicking on a light switch, and the pain is severe, with intense swelling and redness.

Food choices can dictate if you get gout, as high intake of organ meat, shellfish, and alcohol can raise your risk. But diet is only a part of it. "There is a direct relationship between advancing age and gout," says Dr. Robert Shmerling, clinical chief of rheumatology at Beth Israel Deaconess Medical Center.

Ask the doctor

Q. A test showed a 50% blockage in one of my major heart arteries. That sounds pretty bad to me, but the cardiologist said I didn't need a stent. Why?

A . Your reaction is not unusual. Many people find it hard to understand why that degree of blockage wouldn't be treated with a stent—a tiny, flexible mesh tube that props open a newly cleared artery. But while stents can be helpful, they're not risk-free. The procedure to open the artery (angioplasty) involves threading a balloon-tipped tube from the wrist or the top of the thigh up to the heart. Minor risks include discomfort and bleeding at the insertion site. Rare but more serious risks (such as a heart attack) occur in about 3% of people undergoing the procedure. And to prevent blood clots at the stent site, people need to take anti-clotting medications for up to a year afterward.

Peripheral artery disease can be debilitating and dangerous.

Most often, concern about atherosclerosis (when fatty deposits clog arteries) centers on the coronary arteries, which serve the heart. But the arteries outside the heart—the so-called peripheral arteries—are also vulnerable.

When you're active, your leg muscles need extra oxygen. But narrowed arteries in the legs can't deliver enough blood and oxygen to keep up with the demand. The result is pain in the calf, thigh, or buttock while walking that goes away with rest. Known as claudication, it's the classic symptom of peripheral artery disease (PAD). But many people with PAD either don't have symptoms or mistake them for another problem. As a result, PAD often goes unrecognized.

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Devices to treat nighttime breathing problems may help lower blood pressure and reduce the harm to your heart.

Peaceful slumber is often a pipe dream for people with obstructive sleep apnea. More than 25 million Americans have this problem, in which the tongue or throat tissue temporarily blocks the airway during sleep. The resulting pauses in breathing (called apneas) lead to explosive snoring or gasping for breath—sometimes more than 30 times per hour.

Ask the doctor

Q. My right hand goes numb when I open a can or use hand tools. Is this something I need to worry about? Do I have carpal tunnel syndrome?

A. The hand receives its sensory information from three different nerves, and irritation of any of them can lead to numbness. In the hand, numbness is often related to the way that the nerve is compressed or squeezed slightly when you bend your wrist, as happens when you open a can. Excess vibration or repetitive hand motion when you use tools may also cause numbness.

If knee pain and swelling are severe an are not getting better, see your primary care doctor for a thorough evalucation. Image: Thinkstock

Arthritis is not the only possible cause of knee pain, swelling, and disability.