Anxiety Archive

Understanding and treating anxiety can often improve the outcome of chronic disease, such as GI tract problems and heart disease.

With headlines warning us of international terrorism, global warming, and economic uncertainty, we're all likely to be a little more anxious these days. As an everyday emotion, anxiety — the "fight or flight" response — can be a good thing, prompting us to take extra precautions. But when anxiety persists in the absence of a need to fight or flee, it can not only interfere with our daily lives but also undermine our physical health. Evidence suggests that people with anxiety disorders are at greater risk for developing a number of chronic medical conditions. They may also have more severe symptoms and a greater risk of death when they become ill.

The anatomy of anxiety

Anxiety is a reaction to stress that has both psychological and physical features. The feeling is thought to arise in the amygdala, a brain region that governs many intense emotional responses. As neurotransmitters carry the impulse to the sympathetic nervous system, heart and breathing rates increase, muscles tense, and blood flow is diverted from the abdominal organs to the brain. In the short term, anxiety prepares us to confront a crisis by putting the body on alert. But its physical effects can be counterproductive, causing light-headedness, nausea, diarrhea, and frequent urination. And when it persists, anxiety can take a toll on our mental and physical health.

Sometimes the emotional part of cancer is the toughest test.

Any kind of cancer diagnosis is life-changing. There suddenly are many decisions to make about treatments, possible surgery, and recovery. It can be a lot to deal with. But one part of the cancer process that often gets pushed aside is the psychological aspect — how do you manage the many emotions that come with it?

"The natural response to hearing 'cancer' is to feel a surge of anxiety and negative thoughts like 'I'm going to die,'" says Dr. John Peteet, head of the psychosocial oncology fellowship at the Harvard-affiliated Dana-Farber Cancer Institute. "Yet many men are reluctant to admit this and keep their feelings inside, so it's tough to know when they need help with this part of a cancer diagnosis."

Feeling afraid about life issues is common as you age, but if it takes over your life, you may have generalized anxiety disorder (GAD).

 Image: © pixelheadphoto/Thinkstock

Everyone feels afraid or worried at times, but if these feelings begin to take over your life, then you may have crossed over into generalized anxiety disorder (GAD), which is the most common anxiety disorder among older adults, according to the Anxiety and Depression Association of America (ADAA).

"The issue with many older men is they often just endure the discomfort of GAD, or think it's normal, and do not talk about the problem," says Dr. David Mischoulon, director of the Depression Clinical and Research Program at -Harvard-affiliated Massachusetts General Hospital. "However, left alone to manifest, GAD may lead to serious health problems, such as high blood pressure, depression, and addictive behavior like excessive drinking."

A little bit of worry and stress is normal — even beneficial. But chronic anxiety may raise your risk for heart problems.

 Image: © grinvalds/Thinkstock

If you feel anxious now and then, that's perfectly normal. In fact, worrying can spur you to take positive action that may benefit your health, such as getting screening tests or doing regular exercise. But excessive worrying can have the opposite effect.

"Small amounts of anxiety and stress can push people to be more productive. The problem happens when anxiety becomes so overwhelming that you're unable to function normally," says Dr. Christopher Celano, a psychiatrist at the Cardiac Psychiatry Research Program at Harvard-affiliated Massachusetts General Hospital. That level of worry and stress may represent an anxiety disorder, a group of conditions that affect some 40 million adults in this country.

The brain's fear center may trigger inflammation and lead to a heart attack. But stress reduction techniques can break the chain.

 Image: © Cardiology Division, Massachusetts General Hospital

A small, almond-shaped area deep inside the brain called the amygdala is involved in processing intense emotions, such as anxiety, fear, and stress. Now, a new brain-imaging study reveals how heightened activity in the amygdala may trigger a series of events throughout the body that raises heart attack risk.

"This study identifies a mechanism that links stress, artery inflammation, and subsequent risk of a heart attack," says study leader Dr. Ahmed Tawakol, an associate professor of medicine at Harvard Medical School. Earlier animal studies have shown that stress activates bone marrow to make white blood cells. These infection-fighting cells trigger inflammation, a process that encourages the buildup of fatty plaque inside artery walls. "But what we didn't know was, does this happen in humans? And what is the role of the brain?" he says.